The approach of this project was based on the assumption that relevant toxicity data can be extracted from the risk-phrases that have been assigned to the chemical substances and published on official and advisory lists, and that this information can be transformed into one figure representing the level of toxicity. The overall purpose of this project was to facilitate the integration of the assessment of chemical substances in Life Cycle Assessment. This is put into practice by the following tasks: Establish a database with data on human toxicity and ecotoxicity for chemical substances derived from risk-phrases. Establish a software that can calculate effect factors according to the EDIP Methodology from these data. It was furthermore the purpose to apply this model to calculate effect factors for substances present on official - and advisory lists.